Single story, a-frame medical office building with large overhang for cars in the entrance.

South Mississippi Urology

1124 Oakleigh Rd.
Ocean Springs, MS 39564
Get Directions
Call (228) 875-3778

About the Practice

South Mississippi Urology is the premier urology practice in Mississippi and on the Gulf Coast. Our board certified urologists provide the finest urologic care available and strive for the best outcomes for all of our patients.

Combined with over 25 years of experience in treating urological conditions, Dr. Mark Lyell and Dr. David Spencer Jr. provide South Mississippi with convenient care in 3 locations spanning the Mississippi Gulf Coast.


Our experienced team of urologists use state of the art diagnostic equipment and advanced treatment techniques including da Vinci Robot assisted technology and many other laparoscopic and minimally invasive procedures to manage all urological problems in men, women and children.


Adrenal Tumors/Cancer
Benign Prostatic Hyperplasia
Bladder Cancer
Erectile Dysfunction/ED
Kidney Cancer
Kidney Stones
Male Infertility
Peyronie’s Disease
Prostate Cancer
Prostatitis & Prostate Infection
Testicular Cancer
Urethral Stricture Disease
Urinary Incontinence
Urinary Tract Infection
Vasectomy Reversal


Adrenal Tumors/Cancer
Bladder Cancer
Kidney Cancer
Kidney Stones
Pelvic Prolapse
Urinary Incontinence
Urinary Tract Infection
Vesico-Vaginal Fistula Repair

The offices of South Mississippi Urology are closed daily between 12:00 p.m – 1:00 p.m.


Mon: 8:00 am - 5:00 pm
Tue: 8:00 am - 5:00 pm
Wed: 8:00 am - 5:00 pm
Thu: 8:00 am - 5:00 pm
Fri: 8:00 am - 5:00 pm
Sat: Closed
Sun: Closed